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Crystallization and preliminary X-ray analysis of three serotypes of foot-and-mouth disease virus

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dc.contributor.advisor Abu Ghazaleh, Robin
dc.contributor.author Curry, Stephen
dc.contributor.author Abu Ghazaleh, Robin
dc.contributor.author Blakemore, Wendy
dc.contributor.author Fry, Elizabeth
dc.contributor.author Jackson, Terry
dc.contributor.author King, Andrew
dc.contributor.author Logan, Derek
dc.contributor.author Newman, John
dc.contributor.author Stuart, David
dc.date.accessioned 2022-01-18T11:14:09Z
dc.date.accessioned 2022-05-22T08:55:42Z
dc.date.available 2022-01-18T11:14:09Z
dc.date.available 2022-05-22T08:55:42Z
dc.date.issued 1992-12-20
dc.identifier.citation 13. Curry S, Abu-Ghazaleh R, Blakemore W, Fry E, Jackson T, King A, Lea S, Logan D, Newman J, Stuart D. (1992) Crystallization and preliminary X-ray analysis of three serotypes of foot-and-mouth disease virus. J Mol Biol; 228(4):1263-1268. en_US
dc.identifier.other https://doi.org/10.1016/0022-2836(92)90332-E
dc.identifier.uri http://localhost:8080/xmlui/handle/123456789/8388
dc.description.abstract Foot-and-mouth disease viruses from serotypes O, A and C have been crystallized. The particular strains studied include O1K, A1061, A22 Iraq 24/64, A24 Cruzeiro and C-S8c1. In addition, crystals have been grown of G67, a monoclonal antibody neutralization escape mutant derived from O1K, and of virus R100, recovered after the establishment of a persistent infection in baby hamster kidney cells with C-S8c1. Empty particles, capsids which lack the RNA genome, have also been crystallized for subtypes A22 Iraq 24/64 and A1061. In almost all cases, crystals suitable for high resolution structure determination were obtained from (NH4)2S04 or mixtures of polyethylene glycol and NH4Cl. en_US
dc.publisher Academic Press en_US
dc.title Crystallization and preliminary X-ray analysis of three serotypes of foot-and-mouth disease virus en_US
dc.type Article en_US


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