dc.contributor.author | Ayyash, Muneef | |
dc.contributor.author | Tamimi, Hashem | |
dc.contributor.author | Ashhab, Yaqoub | |
dc.date.accessioned | 2020-11-28T07:04:08Z | |
dc.date.accessioned | 2022-05-22T08:28:00Z | |
dc.date.available | 2020-11-28T07:04:08Z | |
dc.date.available | 2022-05-22T08:28:00Z | |
dc.date.issued | 2012-01-23 | |
dc.identifier | 10.1186/1471-2105-13-14 | |
dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/7884 | |
dc.description.abstract | Caspases are a family of cysteinyl proteases that regulate apoptosis and other biological processes. Caspase-3 is considered the central executioner member of this family with a wide range of substrates. Identification of caspase-3 cellular targets is crucial to gain further insights into the cellular mechanisms that have been implicated in various diseases including: cancer, neurodegenerative, and immunodeficiency diseases. To date, over 200 caspase-3 substrates have been identified experimentally. However, many are still awaiting discovery. | |
dc.language.iso | eng | |
dc.source | BMC bioinformatics | |
dc.title | Developing a powerful in silico tool for the discovery of novel caspase-3 substrates: a preliminary screening of the human proteome. | |
dc.type | Journal Article |
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